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By using overexpression and knock out model systems it has been demonstrated that upon treatment with the chemopreventive Nrf2 inducer 3H-1,2-dithiole-3-thione (D3T) the expression of Srx is upregulated and thus prevents the double oxidation of Prx in neurons [79]

Thioredoxin and cancer: a role for thioredoxin in all states of tumor oxygenation

The nanozyme activities could be tuned simply by varying the reaction pH

181 (2008): 6664-69, Strohl, CO Biotechnology 20 (2009): 685-91 ) or also reviewed in Saunders 2019 (Front

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Cancers (Basel) (2021) 13(19):4796