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A nonsignificant tendency of improved fatigue and comprehensive work engagement was also noted in the vitamin C group

Reference Strom, Hager, Seiter, Davis and Riechers2020)

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This finding supports the safety of APE at therapeutic doses, making it a promising candidate for further exploration in anti-inflammatory and antioxidant therapies

The HRMS analysis was performed in the full scan mode of m/z 1001000 with two selected ion monitoring (SIM) windows: 3.94.9 min m/z 221224 and 4.96.3 min m/z 235238

De novo glutamate synthesis occurs by the pyruvate carboxylase, which is located exclusively in astrocytic mitochondria