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Elderly people, people with digestive disorders (leaky gut, IBS, Chrons, etc), people with anemia or heavy menstrual cycles, and vegans/vegetarians are most at risk of having a B12 deficiency

Drawing small volumes from highly concentrated solutions increases measurement errors

Li Y, Li A, Glas M, Lal B, Ying M, Sang Y, Xia S, Trageser D, Guerrero-Cazares H, Eberhart CG, et al

If needed, gently roll the vial between your palms

TB-500 Dosing Math by Vial Size 5 mg vial + 1 mL bacteriostatic water = 5 mg/mL (5,000 mcg/mL) 5 mg vial + 2 mL bacteriostatic water = 2.5 mg/mL (2,500 mcg/mL) 10 mg vial + 2 mL bacteriostatic water = 5 mg/mL (5,000 mcg/mL) The 5 mg/mL ratio (1 mL of water per 5 mg vial) is the most popular setup because the doses land on clean, easy numbers