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doi: 10.1016/j.canlet.2021.09.018

H.SunY.GoodhartD

H.YangB.JungJ

Rodriguez B, Hoepner R, Salmen A, et al

This OS and the breakdown of acetaldehyde can result in the creation of DNA adducts and may be associated with epigenetic modifications of DNA, like methylation [180]

Thus far, evidence from both clinical trials and basic research has revealed several key features of immunopathology in severe COVID-19, including lymphopenia, antibody-dependent enhancement (ADE), neutrophilia, dysregulation of monocytes and macrophages, reduced or delayed type I interferon (IFN-I) response, and CS (Fig