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Kitt is the first-order rate constant for the disappearance of glucose (Kitt) during the 3 to 15 minutes period after intravenous insulin administration, and was taken as a measure of insulin sensitivity, and was calculated as follows: Kitt (%/min)=(0.693100)/t1/2, where t1/2 is the half-life calculated from the slope of the plasma glucose concentration

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Jukic AMZ, Baird DD, Weinberg CR, Wilcox AJ, McConnaughey DR, Steiner AZ

Some individuals prefer lower concentration formulations to reduce injection site discomfort, while others prefer higher concentrations to minimize injection volume

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