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Moreover, the authors suggested that the presence of AHK-Cu may have reduced the number of apoptotic dermal papilla cells

Arch Biochem Biophys 564:5266

Functional enrichment analysis showed that MOTS-c improved angiogenesis, inflammation and apoptosis in terms of cell function, suggesting that MOTS-c may have the same effect as aerobic exercise and improve heart failure in patients with diabetes through NRG1-ErbB4 pathway (14)