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doi: 10.1001/jamaneurol.2023.2169 144 WardellM

Chan ES, Cronstein BN

However, interpretation remains cautious, as reproductive endpoints (ongoing pregnancy, live birth) are inconsistently reported and dosing (commonly 24 g/day), formulations (MI alone vs 40:1 MI: DCI), co-therapies, and trial quality vary widely, prompting calls for larger, standardized, phenotype-stratified studies