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Shai SY, Fishel RS, Martin BM, Berk BC, Bernstein KE Circulation research

Front Cell Neurosci [Internet] Front Cell Neurosci

10.1016/j.freeradbiomed.2010.09.019 Free Radic

Microbiology 159, 24372443

Iron metabolism depends upon absorption from the diet (1-2 mg Fe/d) to compensate for Fe losses from menstrual bleeding and other blood loss [25]

Also, our work is the first (as far as we know) to pinpoint a potential targetable cellular mechanism, where these metabolic changes clearly affect lymphocyte activation and likely the immune response generally, and if systemic could explain the prevalence of fatigue and other symptoms in these two syndromes