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Rationally designed inhibitor targeting antigen-trimming aminopeptidases enhances antigen presentation and cytotoxic T-cell responses

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A potent CysLT1 receptor antagonist, montelukast inhibits the activation of the NF-B pathway and secretion of IL-6 and IL-8 in FLS (165), next to reducing the disease incidence and its activity (166)

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[4] These are separate-trial, cross-study observations, not head-to-head superiority claims in the regulatory sense

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