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Despite the pathogen eradicating role of macrophages, it has also been reported to produce cytokines, enzymes, and ROS, therefore generating cytokine storms

Glutamine also promotes M2 macrophage polarization through the glutamineUDP-GlcNAc pathway

Phys Med Biol 44:3009-3026, 1999

(5) Standard viability assays, including those that quantify cell density and metabolic activity, indicated that tested cultures supported higher fibroblast numbers compared to controls