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Oxidation of the tryptophan 32 residue of human superoxide dismutase 1 caused by its bicarbonate-dependent peroxidase activity triggers the non-amyloid aggregation of the enzyme

People can also have 'normal' levels of B12 in their blood, but be symptomatic - this is known as a functional B12 deficiency

[DOI] [PubMed] [Google Scholar] 87.Matheny RW, Jr, Nindl BC

5.3 Controlled drug release Controlled drug release can prevent premature drug degradation and systemic exposure, enabling precise drug delivery at the target site while maintaining stable local concentrations and minimizing resistance escape

The cells resuspended in binding buffer (50 mM sodium phosphate, 300 mM NaCl and 20 mM imidazole, pH 7.4) were sonicated for 10 min with middle pulse extension on ice

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