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doi: 10.1186/s12860-022-00454-1 153 JinW

Glutathione S-transferase P1 (GSTP1) polymorphism in patients with chronic obstructive pulmonary disease

Furthermore, a sedentary lifestyle has been shown to substantially increase the risk of developing T2D, primarily through mechanisms involving reduced insulin sensitivity and impaired glucose uptake [5]

Among other possibilities of note is the reaction catalyzed by S -nitrosoglutathione (GSNO) reductase (Figure 1), which can produce GSSG from GSH and GSNO