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Next, we determined whether hypoxic condition also influenced these metabolites, because the tumor core cells are well known to be exposed to both hypoxia and nutrient starvation, and hypoxic microenvironment plays a critical role in tumor progression and metastasis [29]

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Like maternal health conditions such as preeclampsia, lack of understanding of the conditions and their multiple clinical symptoms render diagnosis complex

Even the lowest treatments of NiO-NP (10 mg L 1 ) increased ascorbic acid (2.9-folds) and cysteine contents (1.6-folds)

We next explored whether the NRF2 system in SCLC is capable of responding to inhibition of KEAP1, the E3 ligase responsible for regulating NRF2 protein levels