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It classifies DILI as definite, highly probable, probable, possible, unlikely, or excluded. While the scale standardizes assessments, it should not be applied indiscriminately, as it does not establish causality and may lead to biased conclusions in poorly documented cases

observed that p53 limited erastin-induced ferroptosis by promoting the nuclear accumulation of dipeptidyl peptidase-4 (DPP4) and further increasing the expression of SLC7A11 in human colorectal cancer [33]

Therefore, the first visible change is radiance

Dihydroartemisinin remodels macrophage into an M1 phenotype via ferroptosis-mediated DNA damage

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