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Plasma Metabolite Signature Classifies Male LRRK2 Parkinsons Disease Patients

N.MinW.et al (2017)

RESULTS FROM THE ELUCIDATE TRIAL Sudeep Tanwar 1 Walter Gregory 2 The ELUCIDATE Investigators 3 Peter Selby 4 William Rosenberg 5 , 1 Institute for Liver & Digestive Health, 2 Clinical Trials Research Unit (CTRU), Leeds Institute of Clinical Trials Research, 3 UK Secondary Care Gastroenterologists and Hepatologists, 4 Leeds Institute of Molecular Medicine, University of Leeds, UK, 5 University College London Medical School Background: Biomarkers have been validated for the prediction of adverse events in chronic liver disease (CLD) patients with a diagnosis of cirrhosis

This is higher than the recommended Nutrient Reference Value (NRV) because it is specifically designed to help recovery from B12 deficiency by increasing levels in those who are deficient

In addition, the results indicated essential roles of GPX in controlling ROS homeostasis by regulating intracellular H 2 O 2 levels, maintaining GSH/GSSG balance, and promoting antioxidant enzyme activity

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