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Moreover, many tumors including PCa cells shed DNA into the serum or other easily accessible body fluids (e.g., semen, urine), simplifying the detection of GSTP1 epimutations in early tumorigenesis stages

However, the DHA level, the oxidized form of AsA, showed significant increases of 270% in the roots and 193% in the leaves, compared with that in As-alone-treated seedlings ( Figure 4C )

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Mechanistically, DUSP4-mediated phosphorylation of YTHDC1 at threonine residue T148 enhances its binding to SRSF3, thereby reducing nuclear retention of FTH1/FTL mRNA