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Regulation of gene expression Metabolic enzymes influence gene expression through diverse mechanisms

Zileuton, an FDA-approved oral medication for treating asthma, is an ALOX5 inhibitor that exerts neuroprotective effects by blocking ALOX5-mediated glutamate toxicity and ferroptosis in HT22 cells, a mouse hippocampal cell line [301]

A., Kanaki, T., Slominski, A

(2002) Oxidative stress in Portuguese children with Down syndrome

Zhang Y, Li M, Gao X et al (2019) Nanotechnology in cancer diagnosis: Progress, challenges and opportunities

ROS and RNS production following IRI damage results from the complex interplay of multiple cellular pathways