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Therapeutic perturbation of the CoQ 10 redox axis therefore offers an attractive opportunity to sensitize tumors to ferroptotic cell death, particularly when combined with treatments that elevate oxidative stress or lipid peroxidation

Another study revealed that systemic inflammation can directly alter glucose metabolism within the insula and anterior cingulate cortexkey nodes of the interoceptive network (147)

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Roach T, Stggl W, Baur T, Kranner I (2018) Distress and eustress of reactive electrophiles and relevance to light stress acclimation via stimulation of thiol/disulphide-based redox defences