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Bradfords law, which describes the distribution of articles in scientific journals (75) (Figure 4b), where the gray areas represent core journals in the field

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and 32%, respectively

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These changes put the diaphragm at a mechanical disadvantage, resulting in a reduced ability of the diaphragm to generate flow and pressure, increasing respiratory work, and causing diaphragmatic fatigue ( In addition to the negative changes, there are some positive adaptive structural changes in the diaphragm of patients with COPD