mk571 mrp1 glutathione efflux inhibitor MK-571 shifts cellular thiol pools, further potentiating In vitro function and in

In vitro function and in situ localization of Multidrug Resistance associated Protein (MRP)1 (ABCC1) suggest a protective role against methyl mercury induced oxidative stress in the human placenta Archives of Toxicology Springer Nitrogen monoxide (NO) mediated iron release from cells is linked to NO induced glutathione efflux via multidrug resistance associated protein 1 PNAS MRP1 Dependent Extracellular Release of Glutathione Induces Cardiomyocyte Ferroptosis After Ischemia Reperfusion Circulation Research MRP1 modulators synergize with buthionine sulfoximine to exploit collateral sensitivity and selectively kill MRP1 expressing cancer cells ScienceDirect In differentiated HL 60 neutrophil like cells, MRP1 (ABCC1 ) mediated glutathione efflux stimulated by BzATP and P2X7 receptor signalling regulates exosome release through nSMase activity bioRxiv Protection against Oxidative Stress in Beta Thalassemia Hemoglobin E Erythrocytes by Inhibitors of Glutathione Efflux Transporters PLOS One

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