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Serotonin transporters increased after just four weeks of hormone therapy [] The study has shown that testosterone increases the potential binding sites for commonly prescribed antidepressants such as SSRIs in the brain and therefore provides major insights into how sex hormones affect the human brain and gender differences in psychiatric illnesses, says Siegfried Kasper, Head of the University Department of Psychiatry and Psychotherapy at the MedUni Vienna

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OXPHOS activity analysis in skeletal muscle showed typical features of Fe/S-cluster deficiency with decreased activities of complexes I, II, and III, and a decreased activity of the Fe/S-cluster matrix enzyme aconitase [34]

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All therapeutic approaches should consider both the neuroimmune status and metabolic state of the cerebellum, which is characterized by highly proactive microglia under physiological conditions