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With a strong, well-functioning immune system, the body is better equipped to deal with pathogens and maintain overall health

Together, these observations support a model in which pathological consequences of altered melatonin rhythms in asthma may arise from a temporal mismatch between melatonin availability and NRF2-driven redox programs in key immune cell populations such as ILC2s

Med 42 , 3243 (2007)

POI protein of interest the invention includes embodiments of methods of purifying a protein of interest (POI) comprising contacting a first fusion protein comprising the POI fused to the C-terminus of an intein C-fragment with a second fusion protein comprising an intein N-fragment and a purification tag to form a complex between the first fusion protein and the second fusion protein, wherein the purification tag is located at an intein split junction, which is at the C-terminus of the intein N-fragment

Bioinformatics analysis identified LCN2 as the core ferroptosis mediator regulated by upstream transcription factor SPI1

Crti Rev Oral Biol Med 13:155170