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The strongest published finding is from the foundational Biochemical Pharmacology study by Neelakantan et al.: in diet-induced obese mice, daily 5-Amino-1MQ administration produced reductions in body weight, white adipose tissue mass, and adipocyte size without any significant change in food intake

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Weight loss injections are not suitable for everyone and may have potential side effects such as nausea, vomiting, diarrhea, or, in rare cases, more serious complications

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Increasing workforce skill-mix may be a factor, too