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This epigenetic reprogramming is partly linked with other ITC effects: HDAC inhibition by SFN has been associated with the suppression of phase I carcinogen-activating enzymes and the concurrent induction of phase II detoxifiers (118)

Microplastics in sediment cores from Asia and Africa as indicators of temporal trends in plastic pollution

Given the resistance of EGFR-altered tumors to conventional EGFR inhibitors, ongoing research into combination therapies and novel targeted approaches remains critical for improving treatment efficacy in EGFR-mutant GBM