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Hepsin/ mice exhibit exacerbated APAP toxicity, resulting in more severe liver damage, elevated oxidative stress, and higher mortality

In mice treated with the engineered parasite, only 0.08% of the lung surface had metastases, compared to 4.4% in wild-type N

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The differential equation for the concentration of cytosolic cysteine (Cys) is straightforward: The first term on the right is the production of cysteine from cystathionine (Cysta) by CGTL and the second term is the import of cysteine into the cell, which depends on the concentration of cysteine in the blood ([bCys])