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10.1038/nrn1346 Nat

ChemBioChem 13 , 11161120 (2012)

Altered insulin metabolism is a risk factor for metabolic and cardiovascular conditions and has also been implicated in the pathophysiology of AD and PD ( Although vagal afferents do not directly interface with the gut lumen or microbiota, they can be activated by microbial metabolites, thereby transmitting signals to the brain