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SH-SY5Y cells exhibit a distribution of VitB12 in the lysosomes, mitochondria, and cytosol, accounting for approximately 6%, 14%, and 80%, respectively

However, stem cell therapy may not be suitable for everyone, and other health issues, medications, or factors may make it unsuitable for a given patient

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Generally, the schedule for vitamin B 12 replacement is 1 mg daily for a week or 1 mg 3 times a week for 2 weeks, followed by 1 mg per week for 1 month, and then 1 mg per month as maintenance dose.9 Around 1% to 5% of free vitamin B 12 can be absorbed along the entire intestine by passive diffusion

In contrast to the effect of repeated cannabis extract on oxidative stress in brain, the extract did no affect lipid peroxidation or reduced glutathione levels in the liver tissue