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Our group recently demonstrated that redirecting the cytotoxic potential of these preexisting functional bystander T cells toward tumor cells using an engineered oncolytic virus could largely curtail tumor growth and synergistically improve the efficacy of anti-PD-L1 therapy across multiple preclinical tumor models [150]

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Relative expression (RE) was normalized to the 16S rRNA gene, and results are expressed as the fold-expression relative to the level of uninduced condition (log10 RE = 1)

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PMID: 18796312