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This further initiates the transcriptional activation of antioxidant/drug metabolism enzyme genes including HO-1, SOD, quinone oxidoreductase (NQO1), and glutathione peroxidase (GPX), etc

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Clemastine was shown to promote the differentiation of OPCs by activating extracellular signal-regulated kinase (ERK) signaling through the muscarinic receptor in the spinal cord injury model (Du et al., 2022