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The cells lines were cultured in DMEM media supplemented with 10% fetal bovine serum, 2 mM L-glutamine, 1x MEM Non-essential Amino Acid Solution, 0.1 mg/ml streptomycin and 0.1 U/L penicillin

It uses a 16-week escalation ladder so tolerability can be reviewed before the 2.4 mg weekly research-target dose

Any disagreements in the study selection process were resolved by a third person (Dang)

Human data at clinical exposures are limited

Theyre not interchangeable, and neither is universally better

While studies on this population are limited, phentermine use during pregnancy has been associated with a risk of pulmonary hypertension a rare but serious lung disorder