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This study confirmed that macrophages secreted NO to adjacent epithelial cells, preventing phospholipid peroxidation in epithelial cells, thereby inhibiting ferroptosis, while NO expression did not affect intracellular GPX4 levels

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Pharmaceutical Research , 41, 19912014

The researchers conducted a four-week randomized, placebo-controlled trial with 40 night shift workers, providing them a 3-milligram dose of melatonin before their daytime sleep periods