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In 2 compartment models, where the drug equilibrates between blood and (for example) adipose tissue, during elimination there is a sharp initial fall in blood levels followed by a gradual subsequent fall

Furthermore, the most potent neutralizing sera in our study target two nearly overlapping epitopes (AR3/domain B and domain E) that are also present on E2 core (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Stockli J, Zadoorian A, Cooke KC, Deshpande V, Yau B, Herrmann G, et al

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Strategies for Overcoming Developmental Challenges Strategies for overcoming developmental challenges in order to bring these promising treatments into clinical practice include: Personalized Approaches: One way to address the challenges of clinical translation is through personalized medicine