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The trial explored subcutaneous single ascending doses (SAD) from 0.031.50 mg/kg and multiple ascending doses (MAD) from 0.753.0 mg/day

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Melanotan 2 Storage & Handling Storage by Form Form Lyophilized (powder) Temperature -4F (-20C) freezer Duration Long-term (years) Form Lyophilized (powder) Temperature 35.6-46.4F (2-8C) Duration Several months Form Lyophilized (powder) Temperature Room temperature Duration Shipping window (weeks) Form Reconstituted Temperature 35.6-46.4F (2-8C) Duration 2-4 weeks Form Reconstituted aliquots Temperature -4F (-20C) Duration 3-4 months Protect the vial from light, use BAC water (not regular water) for multi-dose handling, and split into single-use aliquots before freezing to avoid repeat thaw cycles

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Fluorescence was subsequently recorded and scored for individuals showing luminal dilation

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