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2025 Jun;15(6):e70385

Moreover, treatment with a reducing agent that prevents disulfide stress, such as tris(2-carboxyethyl)phosphine (TCEP), specifically suppressed glucose deprivation-induced shGDH1 cell death (Extended Data Fig

Importantly, these changes in mitochondrial mass are not related to engagement of apoptosis: inhibition of caspase activity using zVAD-fmk did not prevent increases in mitochondrial abundance per cell (Extended Data Fig

This molecule exists in two states: reduced (GSH) and oxidized (GSSG)

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Vascular Growth and Collateralization Evidence from animal models and cell cultures indicates that BPC-157 may encourage the formation of new blood vessels under ischemic conditions