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We report the discovery of a metabolic phenotype present in HGG that spans genetic and transcriptomic disease subtypes and recapitulates the biology of a rare inborn error of creatine metabolism, GAMT deficiency

The biosynthetic pathway for heme synthesis in E

This cellular architecture enables them to respond to pathogen-associated molecular patterns through transcription and translation, thereby conferring immunocompetence

O.BychkovM

Notably, canonical GPX4 inhibitors, such as RSL3 and ML162, also inhibit thioredoxin reductase 1 (TXNRD1) 121,122

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