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Taken together, the findings suggest that while both interventions provided some degree of short-term symptomatic relief, the mechanical needling and sterile water approach demonstrated superior and longer-lasting efficacy in reducing axial and radicular pain, as well as enhancing ambulatory function, in older patients with lumbar spinal stenosis [63]

Report any new symptoms of fatigue, malaise, low-grade fever, and joint aches

Those who are allergic to Zepbound or Tirzepatide Those with type 1 diabetes Those with a family/personal history of thyroid cancer or thyroid problems People with a history of severe gastrointestinal disease Those with multiple endocrine neoplasia syndrome type 2 (MEN 2) People with disease of the pancreas (pancreatitis) Those with kidney disease Those who are pregnant or planning to become pregnant Those who are breastfeeding Speak with your medical provider before starting Zepbound if you have any of the above conditions or potential concerns

You can find additional information about the risks of FDA-approved medications that contain semaglutide here

Nat Rev Endocrinol 9 , 346356 (2013)

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