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Vitamin B12, also known as cobalamin, is a crucial nutrient that plays a vital role in various bodily functions

Active B12: Each capsule provides 1 mg vitamin B12 as methylcobalamin, which is more efficiently used by the body compared to other forms of vitamin B12, like cyanocobalamin Heart & Brain Health: Supports a normal level of homocysteine in the body to benefit healthy cardiac function, blood cell formation, and optimal nerve function* Sleep Support: Helps maintain normal circadian rhythms to support restful sleep and supports healthy methylation processes in the body* Third-Party Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants Trusted: Thorne is trusted by 100+ professional sports teams and the #1 most recommended clinical brand by consumers and health-care practitioners (Based on a 2026 independent survey of US supplement consumers and health-care practitioners)

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This study also revealed lower levels of glutathione in the anterior cingulate cortex and thalamus, which supports the idea of origin of glutamate from glutathione (16)

Additionally, genetic studies have uncovered a fascinating link: a naturally occurring variant of the MOTS-c peptide (in which a single amino acid, glutamate, is replaced by lysine at a certain position) has been associated with exceptional longevity in some populations

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