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28 Up to 28% of patients with vitamin B12 deficiency experience neuropsychiatric abnormalities even without hematological signs

Low back pain often peaks between ages 50-55, with women reporting it more than men

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Summary: Metformin commonly reduces vitamin B12 levels by interfering with calcium-dependent absorption in the terminal ileum, particularly with long-term use and higher doses

If left untreated, the condition could increase the risk of several complications such as severe skin infections, vision loss and other neurological problems

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