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the present invention specifically relates to each and every combination of features and embodiments described herein, including any combination of general and/or preferred features/embodiments

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Pyruvate kinase M2 (PKM2) has long been portrayed as the main isoform expressed in cancer cells 138,139,140,141,142,143,144,145,146,147 although this notion has been toned down by more recent work 148,149

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