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METTL3 promotes chemoresistance in small cell lung cancer by inducing mitophagy

doi: 10.1007/s00344-022-10752-9 167 ZulfiqarU.AyubA.HussainS.WaraichE

There is a critical c-Myc-binding E-box at 1609/1604 of the human GCLM promoter that in conjunction with the proximal ARE, mediate the full induction of the GCLM promoter when treated with H 2 O 2 (Benassia et al., 2006)

Mitochondrial morphology analysis The mitochondrial morphology of HCC and PCa cells was evaluated by transmission electron microscopy (FEI, Hillsboro, Oregon, USA) as described previously