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More serious B12 deficiencies have the potential to impair heart and neurological function, leading to a wide range of serious symptoms, including but not limited to tinnitus, severe joint pain, memory problems, depression, anxiety, poor muscle function, ataxia and changes in reflexes

Smither also shared insight into his guitar style and technique on two instructional DVDs, available from Homespun Video

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2 mg (2000 mcg) once daily subcutaneously, the FDA-approved regimen, after an optional 1 mg first-week titration