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Available findings indicate that drugs targeting H3K27me3 can effectively inhibit tumor progression and overcome resistance to anticancer drugs, either alone or in combination with other therapies

Data availability Nucleotide sequences of codon-optimized genes can be found in Supplementary Table 6

Prior to the analysis, G422 cells were seeded at a density of 1 10 6 cells/well in a 12-well plate and allowed to adhere and proliferate overnight under optimal culture conditions

We previously discovered that, regardless of its activation state, D2R can enhance the membrane expression of DAT and consequently DAT-mediated reuptake of dopamine through their direct protein-protein interaction [23]

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