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[DOI] [PMC free article] [PubMed] 57.Kaspar JW, Niture SK, Jaiswal AK

PDL-inhibitors include atezolizumab, avelumab, and durvalumab

S2CID 13184375

The key enzyme in this activation pathway is arsenic methyltransferase (AS3MT), which catalyzes the methylation of inorganic arsenic to form metabolites such as monomethylarsonous acid (MMA III ) and Dimethylarsinous acid (DMA III )

Over the past decade, considerable progress has been made in developing pharmacological agonists and antagonists for the treatment of these ferroptosis-related conditions