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Bone marrow-derived mesenchymal stem cells expressing thioredoxin 1 attenuate bleomycin-induced skin fibrosis and oxidative stress in scleroderma

Supplementation with B12 may be advised for these groups, and it can be administered orally, through fortified foods, or by injection in cases where absorption may be impaired

For doses requiring multiple injections, administer consecutively at different sites

Rotate injection sites systematically (abdomen, thighs, upper arms) at least 12 inches apart to reduce local irritation and prevent lipohypertrophy [8]

Schwenk R, Banania G, Epstein J, Kim Y, Peters B, Belmonte M, et al

Patients should consult their healthcare providers to discuss these treatment options, especially considering the potential for side effects with certain combinations, and to determine the best approach for managing their diabetic neuropathy