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Ferroptosis is triggered by inactivation of cellular glutathione (GSH)-dependent antioxidant defenses, leading to the accumulation of toxic lipid ROS (L-ROS) [5, 6] (Fig

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However, much of this information has come from studying non-hematopoietic cells or pathway components in cell-free conditions

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Colchicine-loaded lipid bilayer-coated 50 mesoporous nanoparticles efficiently induce microtubule depolymerization upon cell uptake

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Initiation and Fatty Streak Phase of Atherosclerotic Lesions The endothelial lining of arteries responds to mechanical and molecular stimuli to regulate tone, (4) hemostasis, (5) and inflammation (6) throughout the circulation

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