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Cyclin D1 promotes the progression from the G1 phase to the S phase of the cell cycle, together with cdk4 and cdk6 (156)

For example, nuclear p53 and FOXOs promote ATG expression, whereas cytoplasmic p53 and ATF5 act as autophagy repressors in certain contexts

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Gene-Environment Interactions Perhaps most important is understanding that genes rarely act alone in causing hypertension