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Anti-malaria drug artesunate prevents development of amyloid-beta pathology in mice by upregulating PICALM at the blood-brain barrier

Recent studies suggest that glucose metabolism is a potential therapeutic target for PD

Ascorbate supplementation markedly improves the differentiation of midbrain derived neural stem cell against dopaminergic neurons, which is associated with the TET-mediated 5hmC generation and Jmjd3 catalyzed loss of H3K27m3 (He et al., 2015)

Kinetics of hepatocellular proliferation as a function of the microvascular structure and functional state of the liver

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It upregulates the expression of anti-inflammatory genes, including NF-BIA , MAP3K8 , and TLR5 , while concurrently downregulating pro-inflammatory genes such as TNFSF6 , TNF- , and nuclear factor-B ( NF-B ) [36,37,38,39]