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In a phase 3, double-blind placebo-controlled multicenter trial (n=94), participants with a history of recurrent AHP attacks (2 in the 6 months before enrollment) givosiran (2.5 mg / kg monthly) treatment resulted in a 73% reduction in mean annualized attack rate compared with placebo treatment

& Reginato, M

"CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting"

Maintenance of the mucus layer is very important bacteria must be kept away from the colonic epithelium, otherwise an immune response may be activated, leading to inflammation (11, 12)

With consistent use over time, there can be additional benefits of using a CLA supplement