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By binding to these metabolic waste products and exporting them out of the mitochondria, ALCAR frees up Coenzyme A, ensuring that the Krebs cycle can continue churning out the ATP required for everything from muscle contraction to complex cognitive processing

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Hyperactivity in the PAG, thalamus, ACC, and somatosensory cortex might be one of the final common pathways to symptoms of CIPN, as these brain regions support interoception (Kleckner et al., 2017), the processing and perception of sensations from the body (Khalsa et al., 2018)

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