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B12 is naturally available only in animal proteins, so people who eat vegetarian or vegan diets may not consume enough B12

Gastrointestinal Symptoms: The second most frequent category of adverse events involved digestive system effects

Many energy drinks, protein bars, and meal replacement shakes contain high doses of B12 (sometimes 2,000 to 5,000% of the Daily Value per serving)

[37] Vegetarianspeople who consume animal byproducts such as milk and eggs, but not meat or organsare also at risk

Limitations: The Pivotal Trial Failed This is the central fact that any honest discussion of AOD-9604 must not bury

Importantly, no severe treatment-related adverse effects were documented across any trial